The Path to Success for Advanced-Age Pregnancy 🏆
Among the women in the waiting room, one-third are over the age of 40.
However, it is an undeniable fact that pregnancy rates decrease with age.
The increasing age of women entering fertility treatment has become a common challenge faced by fertility centers in recent years.
So, what is the path to success for advanced-age pregnancy ❓
- Start treatment early:
If you are over 38 years old and your AMH is below 1.2, you should seek professional assistance as soon as possible. - Choose a treatment with a higher success rate:
For IVF treatment in women over 40, the pregnancy rate with frozen embryo transfer can reach 36%, while fresh embryo transfer is only 5.3%, according to assisted reproduction statistics released by the Health Promotion Administration in June 2020.
When fresh embryos are transferred during the treatment cycle, endometrial receptivity may be affected by ovarian stimulation medications, reducing the implantation rate.
Frozen embryo transfer avoids this issue and may result in better pregnancy and live birth rates.
- Preimplantation Genetic Testing for Aneuploidy, PGT-A:
Frozen embryos that have undergone chromosome testing and are confirmed normal have an approximately 70% pregnancy rate after thawing and transfer.
This can help avoid implantation failure caused by abnormal embryos related to advanced maternal age.
This is also another reason why statistics show that older women have higher pregnancy rates with frozen embryo transfer.
In general, fresh embryos are usually transferred without PGT-A testing.
- Choose a personalized treatment plan:
Consult with your physician to determine the best treatment approach based on your individual condition.
The goal is to retrieve as many eggs as possible with the most cost-effective plan, discuss whether PGT-A should be used, and choose the treatment strategy that can help achieve pregnancy as quickly as possible.
- Accumulate eggs or embryos:
Because the number of eggs retrieved at advanced age is usually limited, you may consider accumulating a certain number of eggs or embryos before proceeding with transfer. - Egg donation:
If ovarian function has failed, or repeated egg retrievals and embryo transfers have not succeeded, leaving you physically and emotionally exhausted, you may consider discussing another option with your partner.
After counseling, receiving donated eggs may also open another path forward.
Yun-I wishes you good pregnancy luck!
